Saturday, September 29, 2012

Good idea, elixer of Metformin


Tolerating metformin

Metformin along with lifestyle change is a cornerstone in the treatment of type 2 diabetes, unfortunately many people have trouble tolerating the gastrointestinal side effects associated with metformin.
My usual approach is to start with a low dose , 250 mg daily, and then increase by 250 mg /d every 2 weeks until the recommended dose is reached. If nausea occurs with a dose increase , the person can go back to previous dose and wait 2 more weeks and then try increasing it again. This approach is usually effective .

Good idea , elixer of metformin
I was listening to a diabetes medication discussion by Ann Peters,MD recently.  She has added a useful idea that may be useful for some one unable tolerate  the 250 mg dose.

She has them go to a compounding pharmacy and get an elixer of metformin 50 mg/teaspoon. This allows a person to start the metformin dose titration at 50 mg and then adjust every 2 weeks as discussed above.

Have fun , Be Smart and find a way to take your metformin
David Calder,MD

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Your comments and questions are appreciated. David Calder,MD