Low- Dose aspirin and Cancer mortality: A Meta- Analysis of Randomized Trials
American Journal of Medicine June 2012 , 125 560-567
This study evaluated data from 11 trials reporting cancer mortality in patients taking low -dose aspirin
( 75 to 324 mg ). They compared cancer death among patients taking low dose aspirin and non aspirin users.
Total number of patients -16,066
cancer deaths in patients using aspirin- 162 of 7998 patients ( 2.02% )
cancer Deaths in non - aspirin users - 210 of 8068 patients ( 2.60 % )
Average followup 2.8 years
These studies demonstrate the effect of low dose aspirin for the prevention of cancer mortality can be realized over a short period of time.
They mention another study;
This study reviewed data from 8 different trials and found that aspirin reduced the long term risk of cancer mortality . The effect was observed after only 5 years of observation regardless of aspirin dose or type of cancer.
Rothwell P. et al Effect of Daily aspirin on long term risk of death due to cancer
Lancet 2011; 377: 31-41
Have Fun , Be Smart and talk to your doctor about the pros and cons of aspirin use
David Calder, MD