Position statement of the American Diabetes Association and the European Association for the study of Diabetes
"Overview of the pathogenesis of type 2 diabetes"
The first paragraph points out that a rise in blood sugar is the result of glucose influx exceeding glucose outflow.
They point out that abnormal islet cell function is a feature of the 2 diabetes.
"The functional islet cell incompetence is the main quantitative determinant of hyperglycemia and
progresses over time "
" Importantly , islet cell dysfunction is not necessarily irreversible "
They recognize the value of weight loss , including bariatric surgery , in decreasing insulin resistance
and relieving the secretory burden of the Beta cells.
They also mention the role of the dysfunctional Alpha cells hyper-secreting glucagon resulting in
increased inappropriate glucose release from the liver
Reading page 2 reminds me of one of the best things physicians can offer their patients is , Hope.
" Importantly , islet cell dysfunction is not necessarily irreversible " , provides that little glimmer of hope.
Have fun , Be Smart and thank God for the wonderful medical research
Check out 2 related post from the past
Oct 8,2011 Lessons from my first patient , Hope
Feb 12 , 2012 Glucagon effects your everyday life