Apo-b is an integral part of each LDL cholesterol particle made in the liver . LDL is responsible for carrying cholesterol to tissues in our body. Apo -b is the key opening the door to various cells in those tissues.
LDL cholesterol is the primary tool used to evaluate risk for heart disease. I have discussed some of the problems with LDL measurements in previous post. Dec,11,2011
Basically LDL Cholesterol is produced in our liver in a spectrum of sizes, from small dense particles to large fatty particles. The size of the LDL particle is effected by Triglyceride levels . Triglyceride levels above 150 mg/dl is associated with an increase in small dense LDL putting a person at higher risk of cardiovascular disease .
I will ask you now to find your last lipid panel and do a little math.
* calculate your LDL by subtracting your HDL and 1/5 of your triglycerides from your total cholesterol
* Now add 200 to your triglyceride test result and repeat the calculation. What effect did that have on
your LDL cholesterol result ?
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Have Fun , be Smart , do your math