Metformin ( glucophage) use increases the risk of Vitamin B12 deficiency.
Metformin reduces the absorption of vitamin B12 from our intestinal track.
The effect seems to be dose related.
About 22% of the patients taking metformin developed B12 deficiency. There have been multiple studies with similar results.
The occurrence of B12 deficiency was less in people who took a multivitamin containing B12.
Recommendation for people taking metformin:
#1 Consider routine assessment of B12 levels during long term treatment with metformin
#2 Taking a multiple vitamin containing B12 may reduce the risk of developing B12 deficiency
Have fun , be smart and look up the side effects of every medication you are taking
Tomorrow . Discussion of B12 deficiency