What are the Benefits of A1c testing ?
Glucose in blood binds to hemoglobin in red blood cells and remains attached for the life of the cell which is about 3 months. Higher glucose levels are associated with more glucose attachment . The chart below will give you an idea of how A1c results correlate with mean glucose test results..
Mean plasma glucose
6 126 7.0
7 154 8.6
8 183 10.2
9 212 11.8
10 240 13.4
11 269 14.9
The A1c test is a predictor of the risk for developing diabetes complications. Two classic studies, the DCCT study in Type 1 Diabetes and the UKPDS done with Type 2 Diabetes demonstrated a significant reduction in eye , nerve and kidney damage by reducing the A1c to 7. There was about a 30 % reduction in risk for a 1 % point drop in A1c. There was also a nonsignificant 16% reduction in cardiovascular risk by reducing The A1c from 8 to 7 in the UKPDS .
These two large studies and another one called the Kumamoto study provided the evidence for establishing an A1c result of < 7 as the recommended target goal
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