Time saver hint. Just read the bold print and save 46 seconds for the rest of your day
My neighbor is a 40 y/o female with type 2 diabetes for 4 years and takes glucophage 1000 mg twice a day.She has lost 15 pounds since her diagnosis and walks over 30 minutes almost daily but is still is a little thick in the middle. Recently she has noticed a gradual increase in her home glucose test and an increase in her A1c from 6.8 to 8.1 . She is concerned that her glucophage has stopped working and wants to quit taking it. I explained that her problem is not glucophage . It is still doing it's job . The problem is that her ability to produce insulin has decreased and she will probable need to add another medication.
She has an appointment with her doctor tomorrow to discuss her treatment options.
She is worried because of friends who have gained weight and have had low blood sugars on other diabetes medications . I started with my usual doctor talk below and she stopped me and explained that she does not need to know all of the details at this time.
She is looking for a simple list of the pros and cons of the other medicines that will help her better understand her options before her doctor visit tomorrow. She wants to learn more about the details later.
( Please ignore doctor talk 1,2,3,4 below for now)
Players in the game that effect the decision process.
#1 dysfunctional Beta cells in her pancreas that have sluggish insulin release and are slowly failing
#2 dyfunctional alpha cells in her pancreas in inappropriately producing and releasing glucagon
#3 her tissue resistance to insulin
#4 GLP 1 deficiency
Here is the simple list she requested.
GLP1 agonist DPP4 inhibitors acarbose Insulin sulfonylureas
Effectively reduce A1c YES YES YES YES YES
Preserve Beta cell function YES ? NO NO NO
Promotes weight loss YES NO + - NO NO
Promotes weight gain NO NO + - YES YES
Do not cause hypoglycemia YES YES YES NO NO
Once a week injection YES NO NO NO NO
Most expensive YES +- NO + - NO
What is your first choice if money is not an issue ?
What is your first choice if money is a problem ?
Will GLP-1 Agonist help some one with Type I Diabetes ?
Tomorrow we will start on doctor talk with details about the above medications.
Have fun, Be Smart and Defeat Diabetes